ABSTRACT
Cuando un plan de actividad física se orienta a la reducción de tejido adiposo corporal, es trascendental conocer y manejar los factores que pueden aumentar o reducir la utilización de grasas como energía durante el ejercicio. En el presente estudio se revisa la evidencia actual respecto a factores alimentarios que pueden influir sobre la oxidación de grasa durante el ejercicio, buscando identificar una estrategia nutricional para que el programa de entrenamiento logre un óptimo efecto sobre la mejoría en la composición corporal. Para que una sesión de ejercicio logre una máxima oxidación de grasa se recomienda diseñar planes de alimentación equilibrados, con una restricción moderada en el aporte de carbohidratos, evitar ingerir carbohidratos dentro de las 3 horas previas al ejercicio, elegir una ración de bajo IG previa al ejercicio y evitar ingerir carbohidratos durante un ejercicio de baja intensidad.
Subject(s)
Humans , Male , Female , Fatty Acids/antagonists & inhibitors , Dietary Carbohydrates/administration & dosage , Nutrition Programs , Obesity/diet therapy , Obesity/prevention & control , Exercise , Oxidation-ReductionABSTRACT
The choice of an irrigating solution for use in infected root canals requires previous knowledge of the microorganisms responsible for the infectious process as well as the properties of different irrigating solutions. Complex internal anatomy, host defenses and microorganism virulence are important factors in the treatment of teeth with asymptomatic apical periodontitis. Irrigating solutions must have expressive antimicrobial action and tissue dissolution capacity. Sodium hypochlorite is the most used irrigating solution in endodontics, because its mechanism of action causes biosynthetic alterations in cellular metabolism and phospholipid destruction, formation of chloramines that interfere in cellular metabolism, oxidative action with irreversible enzymatic inactivation in bacteria, and lipid and fatty acid degradation. The aim of this work is to discuss the mechanism of action of sodium hypochlorite based on its antimicrobial and physico-chemical properties.
Subject(s)
Humans , Disinfectants , Root Canal Irrigants , Sodium Hypochlorite , Fatty Acids/antagonists & inhibitors , Bacteria , Dental Pulp Cavity/drug effects , Dental Pulp Cavity/microbiology , Dental Pulp Cavity/pathology , Chloramines , Disinfectants , Phospholipids/antagonists & inhibitors , Enzyme Inhibitors/pharmacology , Lipids/antagonists & inhibitors , Oxidants , Oxidation-Reduction , Periapical Periodontitis , Dental Pulp/drug effects , Dental Pulp/pathology , Root Canal Irrigants , Sodium Hypochlorite , Solubility , VirulenceABSTRACT
Male rats fed an n-6 polyunsaturated fatty acid (PUFA)-rich diet A or an n-3 PUFA-rich diet B were subjected to a surgical thyroidectomy or to a sham-operation (control animals). Thyroidectomy caused a lesser daily increase of body weight in both dietary groups. The diet A rats showed in average greater values of body weight than diet B rats, for control and thyroidectomized animals. After 30 days of experiment thyroidectomy caused no effect on the relative weight (g/100g body weight) of liver in both dietary groups. However, it increased the relative weight) of gastrocnemius (p<0.05) and brain (p<0.001) in both dietary groups, and it decreased the relative weight of heart in both dietary groups, and it decreased the relative weight of heart in diet A (NS) and in diet B (p<0.05) groups. The relative weights of heart, gastrocnemius, liver and brain of control and thyroidectomized rats of diet A groups were lower than respective organs of diet B groups. Thyroidectomy did not affect the level of plasma proteins of diet B rats was higher than diet A rats, for controls or thyroidectomized animals. Iodine uptake by thyroid gland, the plasma level of T3 of diet B control rats were significant higher thand diet A control rats, but the plasma level of T4 of diet A control rats was higher than diet B control rats (NS). These results suggested that the thyroidectomy and or lipid diets may alter the rat development as well the ingestion of antagonist lipid diets may alter thyroid gland functions
Subject(s)
Rats , Animals , Male , Fatty Acids/antagonists & inhibitors , Diet , Thyroid Gland/physiology , Thyroidectomy , Body Weight/etiology , Thyroid Hormones/deficiency , Blood Proteins/analysisABSTRACT
The liver and brain mitochondrial ATPase activity of surgical thyroidectomized male rats fed two antagonist lipid diets, an n06 polyunsaturated fatty (PUFA)-rich diet A or an n-3 PUFA-rich diet B, during 30 days, was different in comparison to the respective controls (sham-operated animals). Thyroidectomy did not change the diet A liver and diet B brain ATPase activity, but it increased the diet B liver ATPase (p<0.001) and decreased the diet A brain ATPase (p<0.001). The ATPase activity was also altered in function of used diets, with the exception of thyroidectomized rats in liver. The ATPase of diet A control rats was higher than the enzyme of diet B control rats in liver (p<0.001) and brain (p<0.001). The ATPase of diet A thyroidectomized rats was higher than the diet B thyroidectomized rats ATPase (p<0.005)